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This compound is a polyethylene glycol (PEG)- and alkyl/ester-based linker suitable for the synthesis of PROTACs (Proteolysis Targeting Chimeras). PROTACs function by connecting two different ligands: one binds to an an E3 ubiquitin ligase, and the other to a target protein, thereby utilizing the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
Peg- and alkyl/ester-based linker
Molecular weight: 264.32
Molecular formula: C12H24O6
Appearance: Liquid
Color: Colorless to light yellow
Used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)
Facilitates targeted protein degradation via the ubiquitin-proteasome system
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GenScript supplies 2 5 ml endotoxin-free tubes (internal diameter 8 mm external diameter 10 mm height 50 mm) with plain end made of research-grade glass GenScript s Endotoxin-free tubes can be applied to dilute or aliquot sample with an especial requirement of endotoxin level ( 0 005 EU/ml) br GenScript Endotoxin-free tubes are provided in encapsulation with pyrogen-free aluminum foil (folded into a package) which sufficiently inhibits the introduction of any contamination such as RNase/DNase br/
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