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This compound is a polyethylene glycol (PEG)- and alkyl/ester-based linker suitable for the synthesis of PROTACs (Proteolysis Targeting Chimeras). PROTACs function by connecting two different ligands: one binds to an an E3 ubiquitin ligase, and the other to a target protein, thereby utilizing the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
Peg- and alkyl/ester-based linker
Molecular weight: 264.32
Molecular formula: C12H24O6
Appearance: Liquid
Color: Colorless to light yellow
Used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)
Facilitates targeted protein degradation via the ubiquitin-proteasome system
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